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doi:10.5664/jcsm.8376

Elevated TMAO levels were connected to severe illness states and a poor prognosis, with higher levels indicating worse outcomes even when controlling for confounders

Compared with those in the control group, the expression of three genes ( PIK3R1 , HIF-1A , and MAPK1 ) was upregulated and that of TLR-4 was downregulated in L-carnitine-treated group, as shown in Figure 8